Appendix Table 4.

Opioid Reduction Outcomes, Sensitivity Sample Excluding Complete Discontinuation Patients with No Further Clinic Visit Following Last Opioid Prescription

Average daily dose at baseline
Total N = 1,465 n (column %)<20 MME N = 634 column %20 to < 50 MME N = 473 column %50 to <90 MME N = 200 column %≥90 MME N = 158 column %
Opioid reduction measures at end of follow-up
    Reduced to 0 MME565 (38.6%)44.3%35.7%33.0%31.0%
    Mean (SD) number of calendar quarters to reduce to zero MME3.0 (1.7)2.7 (1.6)3.1 (1.7)3.6 (1.7)3.9 (1.6)
    Partially reduced MME536 (36.6%)28.2%38.1%40.5%60.8%
    Mean (SD) MME at end of follow-up, among patients with partial reduction28.0 (33.5)7.4 (4.5)18.9 (10.1)36.3 (18.9)76.4 (49.1)
    Did not reduce MME364 (24.9%)27.4%26.2%26.5%8.2%
Average daily dose at end of follow-up
    0 MME565 (38.6%)44.3%35.7%33.0%31.0%
    1 to <20 MME415 (28.3%)46.4%19.7%10.0%5.1%
    20 to <50 MME287 (19.6%)7.7%38.1%18.0%13.9%
    50 to <90 MME133 (9.1%)1.3%6.1%30.5%22.2%
    ≥90 MME65 (4.4%)<1%<1%8.5%27.9%
  • Abbreviation: MME, morphine milligram equivalence.

  • Patient Ns have been suppressed in this table due to some small cell sizes.