Table 1.

Characteristics of Methotrexate Ingestions by Humans

CharacteristicNumber%
Total calls of ingestions111100
Sex
    Male3229
    Female7971
Age (years)
    0 to 181514
    19 to 401514
    41 to 603431
    61 to 803632
    81 to 10087
    Not listed/unknown33
Ingestion type
    Intentional2321
    Unintentional8879
Unintentional subtype
    Dose error1315
    One extra dose4045
    Multiple extra doses2731
    Pediatric exploratory89
    Medication indication listed6962
    Rheumatoid arthritis3855
    Crohn's disease57
    Psoriasis or psoriatic arthritis1420
    Other disease1217
Treatment
    Leucovorin treatment34
    Intentional ingestion1235
    Unintentional ingestion2265
    Sodium bicarbonate18
    Activated charcoal6
    Blood products4
    Steroids1
    Granulocyte stimulating factor2
Course
    Ingestions admitted to hospital41
    Intentional ingestion1741
    Unintentional—dose error25
    Unintentional—one extra dose1127
    Unintentional—multiple extra doses820
    Unintentional—ediatric exploratory37
    Admitted and leucovorin treatment3128
    Intentional ingestion1239
    Unintentional ingestion1961
    Recorded signs of toxicity1211
    Death22