Comparison of Demographics, Lifestyle Factors, Metabolic Abnormalities among Categories of Agreement and Discordance between C-Reactive Protein and Erythrocyte Sedimentation Rate Values
| Factor | Normal CRP Normal ESR (n = 1123) | High ESR Normal CRP (n = 72) | High CRP Normal ESR (n = 208) | High CRP High ESR (n = 69) |
|---|---|---|---|---|
| Sex (male)II | 514 (45.8) | 30 (41.7) | 78 (37.5)* | 33 (47.8) |
| Age (years)¶ | 50 (37–65) | 64 (55–74)‡ | 55 (42–67)† | 64 (49–76)‡ |
| Alcohol consumption (g/week)¶ | 30 (3–130) | 20 (3–85) | 10 (3–90)* | 13 (3–140) |
| Smoking (current)II | 223 (19.9) | 12 (16.7) | 36 (17.3) | 11 (15.9) |
| Physical activity (low)II | 411 (36.6) | 31 (43.1) | 91 (43.8) | 40 (58.0)‡ |
| Body mass index (kg/m2)¶ | 27.2 (23.9–30.6) | 28.1 (25.4–31.7)* | 30.0 (26.2–33.7)‡ | 32.0 (27.0–35.6)‡ |
| Metabolic syndrome (yes)II | 185 (16.5) | 24 (33.3)‡ | 68 (32.7)‡ | 23 (33.3)‡ |
| Serum IL-6 (pg/mL)¶ | <2 (<2–3.0) | 2.2 (<2–4.1) | 3.0 (<2–4.9)‡ | 4.7 (2.3–8.7)‡ |
CRP, C-reactive protein; ESR, erythrocyte sedimentation rate.
↵* P < .05;
↵† P < .01; and
↵‡ P < .001 compared with the reference category (individuals with normal CRP and normal ESR).
fData available for 1472 individuals.
§ High CRP is defined as >0.5 mg/dL (>5 mg/L); high ESR is defined as >20 mm/h for men and >30 mm/h for women.
↵II Figures for sex, smoking, physical activity, and metabolic syndrome are absolute numbers and percentages (within parentheses).
↵¶ Figures for age, alcohol consumption, body mass index, and serum IL-6 are medians and interquartile ranges (within parentheses).