Comparing HSD, hEDS, and Other EDS Disorders
| HSD | hEDS | EDS, Other | |
|---|---|---|---|
| Joint hypermobility | • | • | • |
| Chronic pain | • | • | • |
| Musculoskeletal pain in more than 2 limbs, back ≥ 3 months | • | • | • |
| Recurrent joint dislocations | • | • | • |
| Recurrent hernias, uterine and rectal prolapse | • | • | • |
| Marfanoid habitus | • | • | • |
| Mild skin hyperextensibility, striae, atrophic scarring | • | • | • |
| Skin fragility, pronounced hyperextensibility | • | ||
| Cardiovascular autonomic dysfunction | • | • | • |
| Mild cardiovascular findings (mild mitral valve regurgitation, aortic root dilation) | • | • | |
| Severe cardiovascular findings (aneurysms, arterial rupture) | • | ||
| Positive family history | • | • | |
| Molecular genetic findings | • |
HSD, Hypermobility spectrum disorder; hEDS, hypermobile Ehlers-Danlos syndrome; EDS, Ehlers-Danlos syndrome.