Multivariable Sensitivity Analysis Using Discretized Age and Various Alternative Dichotomization Thresholds for Predictor Variables Related to Intention to Receive COVID-19 Within 1 Month of Regulatory Approval (Alternative Response Variable)
| Alternative Dichotomization | Multivariable Odds Ratio (95% Cl, P Value)* | ||||||
|---|---|---|---|---|---|---|---|
| Concern† | Edu‡ | Health§ | Age 30 to 39 years‖ | Age 40 to 54 years‖ | Age > 54 years‖ | Sex (Men) | Influenza |
| – | – | – | 0.81 (0.66-0.99, .043) | 0.81 (0.66-1.00, .045) | 0.95 (0.76-1.18, .621) | 2.24 (1.88-2.67, <.001) | 2.22 (1.58-3.19, <.001) |
| – | – | Alt | 0.80 (0.65-0.98, .034) | 0.79 (0.65-0.98, .029) | 0.93 (0.75-1.16, .524) | 2.24 (1.88-2.67, <.001) | 2.21 (1.57-3.18, <.001) |
| – | Alt | – | 0.86 (0.70–1.05, .138) | 0.88 (0.72–1.07, .201) | 1.03 (0.83-1.29, .769) | 2.28 (1.92–2.71, <.001) | 2.21 (1.57-3.18, <.001) |
| – | Alt | Alt | 0.85 (0.70–1.04, .120) | 0.86 (0.71–1.06, .157) | 1.02 (0.82–1.27, .848) | 2.28 (1.92–2.72, <.001) | 2.20 (1.56-3.16, <.001) |
| Alt | – | – | 0.83 (0.68-1.02, .079) | 0.84 (0.68-1.04, .108) | 0.97 (0.78-1.21, .796) | 2.27 (1.91–2.71, <.001) | 2.24 (1.59-3.22, <.001) |
| Alt | – | Alt | 0.82 (0.67-1.01, .064) | 0.83 (0.67-1.02, .078) | 0.96 (0.77-1.19, .698) | 2.28 (1.91–2.71, <.001) | 2.23 (1.58-3.20, <.001) |
| Alt | Alt | – | 0.88 (0.72–1.08, .234) | 0.92 (0.75-1.12, .393) | 1.06 (0.86-1.32, .574) | 2.31 (1.94-2.76, <.001) | 2.24 (1.59-3.22, <.001) |
| Alt | Alt | Alt | 0.88 (0.72–1.07, .209) | 0.90 (0.74-1.11, .330) | 1.05 (0.85-1.31, .639) | 2.32 (1.95-2.76, <.001) | 2.23 (1.58-3.20, <.001) |
| Alternative Dichotomization | Multivariable Odds Ratio (95% Cl, P Value)* | |||||
|---|---|---|---|---|---|---|
| Concern† | Edu‡ | Health§ | Direct Interaction | Concern | Education | Health |
| – | – | – | 1.15 (0.99-1.34, .075) | 2.03 (1.75-2.36, <.001) | 1.36 (1.16-1.59, <.001) | 0.86 (0.72–1.03, .113) |
| – | – | Alt | 1.16 (0.99-1.35, .058) | 2.01 (1.73-2.33, <.001) | 1.38 (1.18-1.61, <.001) | 0.85 (0.54-1.31, .470) |
| – | Alt | – | 1.14 (0.98-1.32, .101) | 2.04 (1.75-2.37, <.001) | 1.53 (1.22-1.94, <.001) | 0.86 (0.71–1.03, .095) |
| – | Alt | Alt | 1.15 (0.98-1.33, .081) | 2.02 (1.74-2.35, <.001) | 1.57 (1.25-1.98, <.001) | 0.82 (0.52-1.27, .384) |
| Alt | – | – | 1.11 (0.95-1.29, .185) | 2.73 (2.25-3.33, <.001) | 1.36 (1.16-1.60, <.001) | 0.88 (0.73-1.05, .161) |
| Alt | – | Alt | 1.12 (0.96-1.30, .153) | 2.71 (2.24-3.30, <.001) | 1.38 (1.18-1.61, <.001) | 0.86 (0.55-1.33, .511) |
| Alt | Alt | – | 1.10 (0.94-1.28, .233) | 2.75 (2.27-3.35, <.001) | 1.54 (1.22-1.95, <.001) | 0.87 (0.73-1.04, .138) |
| Alt | Alt | Alt | 1.11 (0.95-1.29, .198) | 2.73 (2.25-3.33, <.001) | 1.57 (1.25-1.99, <.001) | 0.83 (0.53-1.28, .419) |
CI, confidence interval; Edu, educational attainment; Alt, alternative.
↵* Boldface text indicates P < .05.
↵† Concern about becoming infected with COVID-19. Concern was reported on a 5-point Likert scale (extremely, moderately, somewhat, slightly, not at all). The original (–) threshold divides between moderately/somewhat. The alternative threshold divides between somewhat/slightly.
↵‡ Educational attainment was reported on a 6-point Likert scale (some high school, high school graduate, some college, college graduate, Master's degree and Doctoral/Professional degree). The original (–) threshold divides between College graduate/Master's degree. The alternative threshold divides between some college/college graduate.
↵§ Self-reported health status was reported on a 5-point Likert scale (excellent, very good, good, fair, poor). The original threshold (–) divides between very good/good. The alternative threshold divides between good/fair.
↵‖ Odds ratio relative to the reference class, age < 30 years.