Multivariable Sensitivity Analysis Using Discretized Age and Various Alternative Dichotomization Thresholds for Predictor Variables Related to Intention to Receive COVID-19 Within 3 Months of Regulatory Approval
| Alternative Dichotomization | Multivariable Odds Ratio (95% Cl, P Value)* | ||||||
|---|---|---|---|---|---|---|---|
| Concern† | Edu‡ | Health§ | Age 30 to 39 years‖ | Age 40 to 54 years‖ | Age > 54 years‖ | Sex (Men) | Influenza |
| – | – | – | 0.68 (0.55-0.83, <.001) | 0.66 (0.54-0.81, <.001) | 0.75 (0.60–0.94, .012) | 2.41 (1.99-2.93, <.001) | 2.37 (1.76-3.21, <.001) |
| – | – | Alt | 0.67 (0.55-0.83, <.001) | 0.65 (0.53-0.80, <.001) | 0.74 (0.59-0.93, .008) | 2.41 (1.99-2.93, <.001) | 2.36 (1.75-3.19, <.001) |
| – | Alt | – | 0.73 (0.60–0.90, .002) | 0.73 (0.60–0.90, .003) | 0.84 (0.67-1.05, .118) | 2.47 (2.04-3.00, <.001) | 2.36 (1.75-3.19, <.001) |
| – | Alt | Alt | 0.73 (0.60–0.89, .002) | 0.72 (0.59-0.89, .002) | 0.83 (0.66-1.03,.097) | 2.47 (2.05-3.01, <.001) | 2.34 (1.74-3.16, <.001) |
| Alt | – | – | 0.69 (0.56-0.85, <.001) | 0.69 (0.56-0.85, <.001) | 0.75 (0.60–0.95, .016) | 2.59 (2.12–3.16, <.001) | 2.42 (1.79-3.30, <.001) |
| Alt | – | Alt | 0.68 (0.56-0.84, <.001) | 0.68 (0.55-0.83, <.001) | 0.74 (0.59-0.94, .011) | 2.59 (2.12–3.17, <.001) | 2.41 (1.78-3.27, <.001) |
| Alt | Alt | – | 0.75 (0.61–0.92, .005) | 0.76 (0.62–0.94, .009) | 0.84 (0.67-1.06, .136) | 2.65 (2.18-3.24, <.001) | 2.42 (1.79-3.29, <.001) |
| Alt | Alt | Alt | 0.74 (0.60–0.91, .004) | 0.75 (0.61–0.92, .006) | 0.83 (0.67-1.04, .112) | 2.65 (2.18-3.24, <.001) | 2.40 (1.77-3.26, <.001) |
| Alternative Dichotomization | Multivariable Odds Ratio (95% Cl, P Value)* | |||||
|---|---|---|---|---|---|---|
| Concern† | Edu‡ | Health§ | Direct Interaction | Concern | Education | Health |
| – | – | – | 0.91 (0.78-1.07, .253) | 2.40 (2.07-2.79, <.001) | 1.50 (1.28-1.76, <.001) | 0.87 (0.73-1.04, .136) |
| – | – | Alt | 0.92 (0.79-1.07, .296) | 2.38 (2.05-2.76, <.001) | 1.52 (1.30–1.78, <.001) | 0.84 (0.55-1.28, .413) |
| – | Alt | – | 0.90 (0.77-1.05, .189) | 2.42 (2.08-2.81, <.001) | 1.60 (1.29-1.98, <.001) | 0.86 (0.72–1.03, .098) |
| – | Alt | Alt | 0.91 (0.78-1.06, .224) | 2.40 (2.07-2.78, <.001) | 1.63 (1.32–2.02, <.001) | 0.80 (0.52–1.22, .296) |
| Alt | – | – | 0.88 (0.75-1.02, .096) | 3.99 (3.34-4.77, <.001) | 1.51 (1.28-1.77, <.001) | 0.87 (0.73-1.05, .140) |
| Alt | – | Alt | 0.88 (0.76-1.03, .117) | 3.96 (3.31–4.74, <.001) | 1.52 (1.30–1.79, <.001) | 0.83 (0.54-1.27, .377) |
| Alt | Alt | – | 0.86 (0.74-1.01, .066) | 4.01 (3.36-4.80, <.001) | 1.60 (1.29-1.98, <.001) | 0.86 (0.72–1.03, .099) |
| Alt | Alt | Alt | 0.87 (0.74-1.02, .082) | 3.98 (3.33-4.76, <.001) | 1.63 (1.31–2.02, <.001) | 0.79 (0.52–1.21,.268) |
CI, confidence interval; Edu, educational attainment; Alt, alternative.
↵* Boldface text indicates P < .05.
↵† Concern about becoming infected with COVID-19. Concern was reported on a 5-point Likert scale (extremely, moderately, somewhat, slightly, not at all). The original (–) threshold divides between moderately/somewhat. The alternative threshold divides between somewhat/slightly.
↵‡ Educational attainment was reported on a 6-point Likert scale (some high school, high school graduate, some college, college graduate, Master's degree and Doctoral/Professional degree). The original (–) threshold divides between College graduate/Master's degree. The alternative threshold divides between some college/college graduate.
↵§ Self-reported health status was reported on a 5-point Likert scale (excellent, very good, good, fair, poor). The original threshold (–) divides between very good/good. The alternative threshold divides between good/fair.
↵‖ Odds ratio relative to the reference class, age < 30 years.