Table 2.

Association Between Individual Clinical Variables and the Outcome of Mortality

Clinical PredictorsDischarged AliveDeceasedP-value
Categorical variable (n [%])1253189 
Female sex615 (49.1)84 (44.4)0.267
Chronic obstructive pulmonary disease180 (14.4)44 (23.3)0.002
Asthma139 (11.1)23 (12.2)0.754
Diabetes421 (33.6)91 (48.1)<0.001
Cardiovascular disease217 (17.3)56 (29.6)<0.001
Temperature ≥ 39°C69 (5.8)11 (6.0)1
Temperature ≥ 38°C203 (17.0)34 (18.6)0.684
Age (years)  <0.01
 <50396 (32.3)9 (5) 
 50 to 65415 (33.8)42 (23.2) 
 66 to 79270 (22)79 (43.7) 
 >80146 (11.9)51 (28.1) 
Body mass index >=40 kg/m2147 (14.0)27 (15.9)0.604
Body mass index >=30 kg/m2513 (49.0)69 (40.6)0.051
Oxygen saturation < 93%82 (7.0)36 (19.3)<0.001
Respiratory rate ≥ 25 breaths/minute215 (17.9)67 (35.6)<0.001
Respiratory rate ≥ 30 breaths/minute96 (8.0)40 (21.3)<0.001
C-reactive protein
 > 10 mg/dL228 (33.0)77 (67.5)<0.001
 > 15 mg/dL119 (17.2)46 (40.4)<0.001
 > 20 mg/dL42 (6.1)15 (13.2)0.011
 > 40 mg/dL2 (0.3)2 (1.8)0.18
White blood cell count > 10 × 109/mL172 (14.9)60 (33.0)<0.001
Lymphocytes < 0.8 × 109/mL271 (26.0)68 (40.5)<0.001
Neutrophils > 8 × 109/mL145 (13.9)49 (29.2)<0.001
Serum creatinine >= 2.0 mg/dL114 (9.9)66 (36.1)<0.001
Continuous variables (median [interquartile range])
 Age in years59 [44.5, 71]72.5 [64.8, 80]<0.001
 Temperature °C37.2 [36.8, 37.8]37.2 [36.8, 37.8]0.831
 Oxygen saturation97% [95%, 98%]95% [93%, 97%]<0.001
 Respiratory rate (breaths/minute)20 [18, 23]20 [18, 27]<0.001
 White blood cell count (× 109/mL)6.1 [4.6, 8.1]7.5 [5.5, 11.8]<0.001
 Lymphocytes (× 109/mL)1.1 [0.8, 1.5]0.8 [0.6, 1.3]<0.001
 Neutrophils (× 109/mL)4.4 [3, 6.2]5.9 [4, 8.7]<0.001
 Body mass index (kg/m2)29.8 [25.3, 35.8]28.5 [24.6, 35.8]0.254
 Serum creatinine (mg/dL)0.9 [0.8, 1.3]1.5 [1.1, 2.7]<0.001
 C-reactive protein (mg//dL)6.2 [2.4, 12.3]13 [9, 17.3]<0.001
 Lactate dehydrogenase (U/L)313 [241, 409]441 [349, 590]<0.001