Demographics among Down syndrome (DS) Sample and General Population
| Demographic Factors | DS Sample | General Population Estimates* |
|---|---|---|
| Age, years | n = 2342 | n = 244,652,666 |
| 18 to 29 | 652 (27.84%) | 53,199,212 (21.74%)† |
| 30 to 39 | 406 (17.34%) | 41,412,561 (16.93%) |
| 40 to 49 | 437 (18.66%) | 41,412,561 (16.93%) |
| 50 to 59 | 553 (23.61%) | 43,642,468 (17.84%) |
| 60 to 69 | 268 (11.44%) | 34,085,723 (13.93%) |
| 70 to 79 | 26 (1.11%) | 19,113,489 (7.81%) |
| 80+ | 0% | 11,786,652 (4.82%) |
| Sex | n = 2342 | n = 245,736,019 |
| Male | 1085 (46.33%) | 119,945,724 (48.60%) (>=18) |
| Female | 1257 (53.67%) | 125,790,295 (51.40%) (>=18) |
| Race | n = 2342 | n = 318,558,162 |
| Caucasian | 1419 (80.03%) | 233,657,078 (73.30%) |
| African American | 151 (8.52%) | 40,241,818 (12.60%) |
| American Indian/Alaska Native | 1 (0.06%) | 2,597,817 (0.80%) |
| Asian | 36 (2.03%) | 16,614,625 (5.20%) |
| Other‡ | 166 (9.36%) | 25,446,824 (8.10%) |
| Ethnicity | n = 2342 | n = 318,558,162 |
| Hispanic or Latino | 136 (7.67%) | 55,199,107 (17.30%) |
| Not Hispanic or Latino | 1586 (89.45%) | 263,359,055 (82.70%) |
| Declined | 51 (2.88%) | — |
↵* The 2016 entire general population (n = 318,558,162) was provided, with associated percentages across described age groups. These percentages were used to calculate raw numbers and adjusted percentages of adults ≥ 18 years only (n = 244,652,666). Race and ethnicity represent the entire general population, including youth.
↵>† General population heart disease, stroke and associated risk condition prevalence throughout this paper represent adults ages ≥ 20 years. Adults ages 20 to 29 years make up 18.23%, or 44,598,142 individuals, of the general adult population.
↵‡ Other represents individuals who identified as “Unknown” or “Declined” among DS sample and as “Native Hawaiian and Other Pacific Islander,” “Some Other Race” or “Two or More Races” among general population. The following results will describe OR with associated P-values comparing prevalence of the following heart disease-related conditions among adults with DS to the general population: Coronary heart disease (CHD), Angina, myocardial infarction (MI), and HF, Stroke, diabetes mellitus (DM), Hypertension, Overweight Status, and High total cholesterol (TC). See Table 2 for complete results and Figure 1 for a mapping of the odds ratios (ORs).