Subgroup Analysis with Exclusion of Varying Levels of Baseline HbA1c Control
| n | Baseline, Mean ± SD | Follow-up, Mean ± SD | Change, Mean (95% CI) | P Value | |
|---|---|---|---|---|---|
| Baseline HbA1c ≥ 7% | |||||
| Usual care, HbA1c, % | 222 | 8.50 ± 1.53 | 8.03 ± 1.56 | 0.47 (0.28 to 0.66) | < .0001 |
| Collaborative care, HbA1c, % | 355 | 9.68 ± 2.00 | 7.79 ± 1.60 | 1.89 (1.65 to 2.13) | |
| Baseline HbA1c ≥ 8% | |||||
| Usual care, HbA1c, % | 119 | 9.47 ± 1.52 | 8.56 ± 1.72 | 0.90 (0.62 to 1.18) | < .0001 |
| Collaborative care, HbA1c, % | 284 | 10.24 ± 1.84 | 7.96 ± 1.60 | 2.29 (2.02 to 2.55) | |
| Baseline HbA1c ≥ 9% | |||||
| Usual care, HbA1c, % | 63 | 10.42 ± 1.54 | 9.14 ± 1.95 | 1.28 (0.82 to 1.73) | < .0001 |
| Collaborative care, HbA1c, % | 204 | 10.95 ± 1.70 | 8.11 ± 1.71 | 2.84 (2.51 to 3.17) | |
HbA1c, glycosylated hemoglobin; SD, standard deviation; CI, confidence interval.
All data represented includes subjects originally matched for primary analysis with subjects excluded based on baseline HbA1c values. Subjects included in the subgroup with baseline HbA1c ≥ 9% are included in all three subgroup analyses based on meeting baseline HbA1c for each group. Subjects with baseline HbA1c of ≥ 8% are included in subgroup analyses with baseline HbA1c of ≥ 8% and ≥ 7%.