Appendix Table 1.

Opioid-Prescribing Protocol Elements, Opioid Fill Information, and Co-Medications, for Patients with a PHQ≥10 With any Opioid Prescription in Pre- or Post-Intervention Period

Pre-intervention (n = 441)Post-intervention (n = 476)P-value
Protocol elements
    Urine drug screen95 (21.5%)164 (34.5%)<.0001
    ORT completedn/a45 (9.5%)n/a
    COMMn/a33 (6.9%)n/a
    Opioid Treatment Agreement66 (15.0%)84 (17.7%).273
No. elementsn/a
    0n/a298 (62.6%)
    1n/a93 (19.5%)
    ≥2n/a85 (17.9%)
No longer on opioid158 (35.8%)n/an/a
Still on opioid283 (64.2%)n/an/a
Opioid fill information
Total No. RX, mean (±SD)9.2 (±11.0)8.4 (±8.9).217
Total No. RX, categories
    1128 (29.0%)152 (31.9%)
    260 (13.6%)50 (10.5%).444
    322 (5.0%)27 (5.7%)
    ≥4231 (52.4%)247 (51.9%)
Max daily dose (MED)*(n = 439)(n = 474)
    1 to 50 mg379 (86.3%)407 (85.9%)
    51 to 100 mg50 (11.4%)55 (11.6%).963
    >100 mg10 (2.3%)12 (2.5%)
Co-medications
    Tramadol102 (23.1%)91 (19.1%).136
    Benzodiazepines164 (37.2%)175 (36.7%).894
    Antidepressants335 (76.0%)360 (75.6%).906
    Musculoskeletal agents170 (38.6%)171 (35.9%).411
    Anticonvulsants136 (30.8%)161 (33.8%).335
  • COMM, current opioid misuse measure; MED, morphine-equivalent dose; ORT, opioid risk tool; RX, prescription; SD, standard deviations; PHQ, patient health questionnaire.

  • * Excludes methadone prescriptions.