Table 2.

Opioid-Prescribing Protocol Elements, Opioid Fill Information, and Co-Medications, for Patients with Any Opioid Prescription in Pre- or Post-Intervention Period

Pre-Intervention (n = 1887)Post-Intervention (n = 1532)P-Value
Protocol elements
    Urine drug screen345 (18.3%)411 (26.8%)<.0001
    ORT completedn/a90 (5.9%)n/a
    COMMn/a73 (4.8%)n/a
    Opioid treatment agreement214 (11.3%)189 (12.3%).369
No. of elementsn/a
    0n/a1080 (70.5%)
    1n/a274 (17.9%)
    ≥2n/a178 (11.6%)
No longer on opioid1,075 (57.0%)n/an/a
Still on opioid812 (43.0%)n/an/a
Opioid fill information
    Total No. RX, mean (±SD)7.3 (±10.2)7.2 (±8.8).766
    Total No. RX, categories
        1710 (37.6%)585 (38.2%)
        2281 (14.9%)194 (12.7%).273
        3113 (6.0%)102 (6.7%)
        ≥4783 (41.5%)651 (42.5%)
Max daily dose (MED)*(n = 1883)(n = 1527)
    1 to 50 mg1657 (88.0%)1331 (87.2%)
    51 to 100 mg176 (9.4%)153 (10.0%).762
    >100 mg50 (2.7%)43 (2.8%)
Co-medications
    Tramadol404 (21.4%)257 (16.8%).0006
    Benzodiazepines489 (25.9%)375 (24.5%).336
    Antidepressants1056 (56.0%)791 (51.6%).012
    Musculoskeletal agents580 (30.7%)453 (29.6%).460
    Anticonvulsants450 (23.9%)402 (26.2%).108
  • COMM, current opioid misuse measure; MED, morphine-equivalent dose; ORT, opioid risk tool; RX, prescription; SD, standard deviations.

  • * Excludes methadone prescriptions.