Hydroxyurea (HU) Prescription (Rx) Fills and Adherence for North Carolina Medicaid Enrolled at least 12-monthnths Age 1 to 64 (N = 2013)
| Medicaid Enrolled for 12-monthnths by Age Group | ||||||
|---|---|---|---|---|---|---|
| 1 to 9 (n = 499) | 10 to 17 (n = 436) | 18 to 30 (n = 537) | 31 to 45 (n = 347) | 46 to 64 (n = 194) | All (n = 2013) | |
| Participants with a HU Rx Filled | ||||||
| N (% of eligible sample) | 200 (40.08) | 201 (46.10) | 183 (34.08) | 43 (12.39) | 22 (11.34) | 649 (32.24) |
| Description of usage for participants with at least one HU Rx Enrolled in Medicaid for 12-months | ||||||
| 1 to 9 (n = 200) | 10 to 17 (n = 201) | 18 to 30 (n = 183) | 31 to 45 (n = 43) | 46 to 64 (n = 22) | All (n = 649) | |
| Number of HU Rx Filled | ||||||
| Median (IQR) | 7 (4, 10) | 6 (4, 8) | 4 (1, 7) | 4 (2, 7) | 5.5 (2, 10) | 5 (2, 8) |
| Number of Days Supplied† | ||||||
| Median (IQR) | 221 (104.5, 319) | 180 (105, 270) | 110 (30, 210) | 120 (58, 210) | 165 (90, 300) | 159 (85, 270) |
| Duration of HU Treatment (days)‡ | ||||||
| Median (IQR) | 340 (301, 349) | 334 (285, 350) | 322 (266, 345) | 336 (305, 347) | 334 (287, 357) | 334 (284, 349) |
| Number of Days between breaks in treatment§ | ||||||
| Median (IQR) | 14.21 (0, 50.75) | 22.8 (7.75, 51.50) | 49.33 (19.67, 139) | 40.40 (21.60, 103.50) | 35.45 (0, 89.67) | 29.6 (7, 72.5) |
| HU Adherence¶, n (%) | ||||||
| Good | 95 (47.50) | 60 (29.85) | 33 (18.03) | 9 (20.93) | 8 (36.36) | 205 (31.59) |
| Fair | 30 (15.00) | 48 (23.88) | 23 (12.57) | 8 (18.60) | 2 (9.09) | 111 (17.10) |
| Poor | 75 (37.50) | 93 (46.27) | 127 (69.40) | 26 (60.47) | 12 (54.55) | 333 (51.31) |
IQR, interquartile ranges
* There were zero participants on HU in the 65+ age group so they were excluded from this analysis.
↵† Number of days supplied is the sum of the days of supply on the Rx (eg, 30-day supply) in a 12-month period per person.
↵‡ Duration of HU treatment days is the number of days between the first HU Rx filled and February 28, 2017.
↵§ Number of days between breaks in treatment is the sum of days of no HU coverage divided by the number of gaps (missing next HU Rx fill) per person.
↵¶ HU adherence is considered Good—if number of days supplied is ≤80% of duration of HU treatment; Fair or Moderate—if number of days supplied is 60% to 79% of duration of HU treatment; Poor—if number of days supplied is >60% of duration of HU treatment.