Appendix 1.

Prevalence of Criterion Standards, by Age Group and Gender

	Females						Males
	Age 12 to 15 Years		Age 16 to 17 Years		Age 18 to 20 Years		Age 12 to 15 Years		Age 16 to 17 Years		Age 18 to 20 Years
	N = 38,795		N = 20,825		N = 24,559		N = 40,375		N = 21,531		N = 23,901
	N	(%)	N	(%)	N	(%)	N	(%)	N	(%)	N	(%)
Tobacco Dependence	507	(1.2)	1200	(4.9)^*	2891	(10.5)^†	492	(1.1)	1388	(5.6)	3359	(13.1)
AUD	1068	(2.6)^†	1688	(7.4)	2822	(11.2)^†	713	(1.6)	1626	(7.1)	3668	(14.9)
Any AUD Symptom	2107	(5.1)^†	3637	(16.6)	6383	(25.7)^†	1,689	(3.9)	3627	(16.4)	7711	(31.6)
CUD	773	(1.8)	1146	(5.1)^†	1220	(5.1)^†	736	(1.7)	1587	(7.2)	2104	(8.6)
Any CUD Symptom	1349	(3.1)^*	2358	(10.6)^†	3260	(13.5)^†	1,543	(3.6)	3369	(15.2)	5274	(21.9)
DUD	624	(1.4)^†	554	(2.5)^*	680	(2.7)^†	352	(0.8)	450	(2.0)	803	(3.3)
Any DUD Symptom	1278	(3.0)^†	1089	(5.1)^*	1329	(5.4)^†	836	(2.1)	954	(4.3)	1561	(6.3)

AUD, alcohol use disorder; CUD, cannabis use disorder; DUD, other illicit drug use disorder.
Ns are unweighted, proportions are weighted to account for complex survey design.
χ² test for independence (comparing females and males, within same age group),
↵* P < .01,
↵† P < .0001.