Appendix Table 2.

External validation for the prediction of incident symptomatic knee Osteoarthritis (OA) in Rotterdam Study-III-1

Selected PredictorsStudy Population (n = 264)
OR (95% CI)P Value
Age (years)1.13 (0.93–1.37).22
BMI (kg/m2)1.09 (0.97–1.22).15
Mild knee symptoms*1.53 (0.49–5.08).44
Knee problems while climbing stairs4.47 (1.31–15.23).02
Morning stiffness2.14 (0.68–6.73).19
Postmenopausal status1.33 (0.22–7.98).76
Physically demanding work§1.50 (0.50–4.53).48
AUC of the model0.81 (0.71–0.90)
Calibration: Hosmer-Lemeshow P value.17
Variance explained (Nagelkerke), %21.9
  • AUC, area under the curve of the receiver operating characteristic; BMI, body mass index; CI, confidential interval; OR, odds ratio.

  • Bold indicates P < .05.

  • * Pain in or around the knee within the last 12 months.

  • Defined with the Knee Injury and Osteoarthritis Outcome Score (KOOS) on physical functioning.

  • Defined with the KOOS on stiffness.

  • § Defined as doing intense work (regularly lifting heavy objects at work).