History of Atopy and Allergic Comorbidities by Atopic Dermatitis Status*
| Comorbidity | Overall (n = 652) | AD (n = 159) | No AD (n = 493) | Age-Adjusted Prevalence Ratio | P value | ||||
|---|---|---|---|---|---|---|---|---|---|
| % | 95% CI | % | 95% CI | % | 95% CI | PRa | 95% CI | ||
| Asthma | 7 | (5–8) | 12 | (9–16) | 4 | (3–6) | 3.0 | (1.8–4.9) | <.001 |
| Wheezing without cold | 6 | (4–9) | 9 | (6–13) | 5 | (3–8) | 1.8 | (1.1–2.7) | .011 |
| Wheezing (ever) | 21 | (18–23) | 26 | (19–33) | 19 | (16–22) | 1.4 | (1.02–1.9) | .038 |
| Food allergy | 4 | (3–5) | 8 | (4–12) | 2 | (1–3) | 3.7 | (1.5–9.2) | .005 |
| Family history of atopic condition | 69 | (63–75) | 82 | (74–90) | 65 | (59–71) | 1.3 | (1.2–1.4) | <.001 |
| Parent with asthma | 31 | (25–37) | 36 | (28–44) | 29 | (24–35) | 1.2 | (1.01–1.5) | .037 |
AD, atopic dermatitis; CI, confidential interval; PR, prevalence ratio.
↵* Percents are marginal predictions and prevalence ratio is the exponentiated coefficient from a log-binomial (relative risk) model for the comorbidity including AD and age (months) as predictors. P values are from the Wald test for AD vs no AD.