Distribution of Sociodemographics, Covariates, and 5-Year (2010–2015) Cumulative Incidence of Hypertension Among Adult Primary Care Patients, Overall and by ADM Exposure (n = 6244)
| Variable | Total (n = 6244) | No ADM (n = 4182) | ADM-BP− (n = 1008) | ADM-BP+ (n = 1054) | P Value |
|---|---|---|---|---|---|
| Hypertension, cumulative incidence | 774 (12.4) | 507 (12.1) | 125 (12.4) | 142 (13.5) | .494 |
| Age (years), mean (SD) | 46.4 (15.6) | 46.0 (16.0) | 47.2 (15.7) | 47.2 (13.8) | .012 |
| White race | 4297 (68.8) | 2713 (64.9) | 772 (76.6) | 812 (77.0) | <.0001 |
| Female sex | 3949 (63.2) | 2449 (58.6) | 706 (70.0) | 794 (75.3) | <.0001 |
| Married | 2968 (47.5) | 2058 (49.2) | 426 (42.3) | 484 (45.9) | <.001 |
| High neighborhood SES | 3649 (58.4) | 2378 (56.9) | 618 (61.3) | 653 (62.0) | .001 |
| High clinic utilization | 1380 (22.1) | 628 (15.0) | 297 (29.5) | 455 (43.2) | <.0001 |
| Current smoker | 1164 (18.6) | 620 (14.8) | 214 (21.2) | 330 (31.3) | <.0001 |
| Substance use disorder | 190 (3.0) | 65 (1.6) | 51 (5.1) | 74 (7.0) | <.0001 |
| Depression | 771 (12.4) | 24 (0.6) | 337 (33.4) | 410 (38.9) | <.0001 |
| Any anxiety disorder | 665 (10.7) | 92 (2.2) | 289 (28.7) | 284 (26.9) | <.0001 |
| Obese | 2365 (37.9) | 1480 (35.4) | 413 (41.0) | 472 (44.8) | <.0001 |
| Hyperlipidemia | 1429 (22.9) | 898 (21.5) | 261 (25.9) | 270 (25.6) | .001 |
| Type 2 diabetes | 391 (6.3) | 228 (5.4) | 79 (7.8) | 84 (8.0) | .001 |
| Vascular disease | 605 (9.7) | 356 (8.5) | 110 (10.9) | 139 (13.2) | <.0001 |
Data are n (%) unless otherwise indicated.
ADM, antidepressant medication; BP−, no effect on blood pressure; BP+, increases blood pressure; SD, standard deviation; SES, socioeconomic status.