Survival Models, Hazard Ratios, and 95% Confidence Intervals of the Relationship of Antidepressant Medication Treatment Group and Time to Incident Hypertension among Adult Primary Care Patients (n = 6244), 2010–2015*
| Crude HR (95% CI) | Overall adjusted HR (95% CI) | |
|---|---|---|
| ADM | ||
| None | 1.00 | 1.00 |
| BP− | 1.10 (0.90–1.34) | 1.08 (0.87–1.33) |
| BP+ | 1.30 (1.08–1.57) | 1.20 (0.97–1.49) |
| Age | 1.04 (1.03–1.05) | |
| White race | 0.60 (0.52–0.71) | |
| Female sex | 0.93 (0.80–1.08) | |
| Married | 1.08 (0.93–1.26) | |
| High neighborhood SES | 0.93 (0.79–1.09) | |
| High clinic utilization | 1.37 (1.17–1.61) | |
| Current smoker | 1.43 (1.21–1.70) | |
| Substance use disorder | 1.19 (0.80–1.76) | |
| Depression | 0.88 (0.68–1.13) | |
| Any anxiety disorder | 0.90 (0.68–1.18) | |
| Obese | 1.78 (1.54–2.07) | |
| Hyperlipidemia | 1.07 (0.91–1.26) | |
| Type 2 diabetes | 1.62 (1.31–1.99) | |
| Vascular disease | 0.99 (0.81–1.22) |
ADM, antidepressant medication; BP−, no effect on blood pressure; BP+, increases blood pressure; CI, confidence interval; HR, hazard ratio; SES, socioeconomic status.
↵* ADM treatment and comorbidities were treated as time-dependent variables.