Table 2.

Assessment of Study Quality Using the QUADAS-2 Framework

StudyConsecutive or Random Sample Enrolled (Y/N/U)Avoided Case-Control Design (Y/N/U)Avoided Inappropriate Exclusion Criteria (Y/N/U)Likelihood That Patient Selection Could Have Introduced Bias (H/L/U)Concerns Exist That Included Patients and Setting Do Not Match the Review Question (Y/N/U)Index Test Results Were Interpreted Without Knowledge of Reference Standard (Y/N/U)Likelihood That Conduct or Interpretation of Index Test Introduced Bias (H/L/U)Applicability: Concerns Exist That the Index Test Differs from the Review Question (Y/N/U)Reference Standard Is Likely to Correctly Classify Patients as Having Pertussis (Y/N/U)Reference Standard Was Interpreted without Knowledge of Index Test (Y/N/U)Likelihood That Conduct or Interpretation of Reference Standard Introduced Bias (H/L/U)Applicability: Concerns Exist That the Target Conditions Defined By the Reference Standard Do Not Match the Review Question (Y/N/U)All Patients Received a Reference Standard (Y/N/U)All Patients Received the Same Reference Standard (Y/N/U)All Patients Were Included in the Analysis (Y/N/U)Patient Flow Could Have Introduced Bias (H/L/U)Overall Assessment of Risk of Bias (L/M/H)
Teepe, 2015YYYLNYLNYYLNYYYLL
Karagul, 2015YYYLNYLNYULNYYYLL
Park, 2014YYYLNYLNYULNYYYLL
Gentile, 2014YYYLNYLNYULNYNYLL
Miyashita, 2013YYYLNYLNYULNYYYLL
Ghanaie RM, 2010YYYLNYLNYULNYYYLL
Park, 2005YYYLNYLNYULNYYYLL
Heininger, 2000YYYLNYLNYULNYYYLL
Heininger, 1997YYYLNYLNYULNYYYLL
Granstrom, 1991YYYLNYLNYULNYYYLL
Strebel, 2001YYYLNYLNYULNYNYLL
Gilberg, 2002YYYLNYLNYULNYNYLL
He, 1998YYYLNYLNYULNYYYLL
Heininger, 1993YYYLNYLNYULNYYYLL
Schlapfer, 1995NYYHNYLNYULNYYYLM
Philipson K, 2013YYYLNYLNNUHNYYYLM
Harnden, 2006YYYLNYLNNUHNYYYLM
Senzilet, 2001UYYUNYLNYULNYYYLM
Narkeviciute I, 2005YYYLNYHNNUHNYYNHH
Liese JG, 2003YYYLNYLNNUHNYNNHH
Postels-Multani, 1995NYYHNYLNNUHNYNNHH
Preziosi and Halloran, 2003YYYLNYLNNUHNYNNHH
  • H, high; L, low; M, medium; N, no; U, unknown; Y, yes.