RT Journal Article
SR Electronic
T1 Almond “Appetizer” Effect on Glucose Tolerance Test (GTT) Results
JF The Journal of the American Board of Family
                Medicine
JO J Am Board Fam Med
FD American Board of Family Medicine
SP 759
OP 766
DO 10.3122/jabfm.2016.06.160128
VO 29
IS 6
A1 Crouch, Michael A.
A1 Slater, Robert T.
YR 2016
UL http://www.jabfm.org/content/29/6/759.abstract
AB Background: The extent to which glucose intolerance can be acutely improved with dietary modification is unclear. The purpose of this study was to test the effect of ingesting a low-calorie almond preload (“appetizer”) 30 minutes before oral glucose tolerance testing in glucose-intolerant individuals without diabetes.Methods: Twenty adults with prediabetes or isolated 1-hour glucose ≥160 mg/dL underwent 2 fasting oral glucose tolerance tests (GTTs)—1 standard GTT and 1 GTT 30 minutes after eating a half ounce (12) of dry-roasted almonds. Fourteen participants met 1 or more prediabetes diagnostic criteria; 6 had only elevated 1-hour glucose ≥160 mg/dL.Results: The mean 1-hour plasma glucose after the almond preload was 37.1 mg/dL (19.4%) lower (154.6 vs 191.7; P < .001) than in the standard GTT. The almond preload reduced the area under the glucose curve by 15.5% (P < .001). Eight individuals had a marked hypoglycemic effect (glucose reduced by 45 to 110 mg/dL); 4 had a moderate hypoglycemic effect (22–32 mg/dL).Conclusion: A low-calorie almond “appetizer” showed promise as an option for decreasing postprandial hyperglycemia in individuals with prediabetes or isolated 1-hour postprandial hyperglycemia. Further study is needed to confirm and refine the role of such a premeal appetizer in the self-care of prediabetes.