PT  - JOURNAL ARTICLE
AU  - Arch G. Mainous III
AU  - Rebecca J. Tanner
AU  - Stephen D. Anton
AU  - Ara Jo
TI  - Low Grip Strength and Prediabetes in Normal-Weight Adults
AID  - 10.3122/jabfm.2016.02.150262
DP  - 2016 Mar 01
TA  - The Journal of the American Board of Family
                Medicine
PG  - 280--282
VI  - 29
IP  - 2
4099  - http://www.jabfm.org/content/29/2/280.short
4100  - http://www.jabfm.org/content/29/2/280.full
SO  - J Am Board Fam Med2016 Mar 01; 29
AB  - Introduction: Detection of prediabetes is an important step in diabetes prevention in primary care. Risk stratification of healthy-weight individuals for detection of prediabetes is necessary to avoid missed opportunities for diabetes prevention.Methods: Using data from the 2011 to 2012 National Health and Nutrition Examination Survey, we studied the relationship between combined handgrip strength, a proxy for lean muscle mass, and prediabetes among adults aged ≥20 years without diagnosed or undiagnosed diabetes who had a healthy body mass index (18.5–24.9 kg/m2; unweighted n = 1340, weighted n = 58,360,690). Prediabetes was defined as having a glycohemoglobin level between 5.7% and 6.4%.Results: Of the healthy-weight adults, 20.5% had prediabetes. Combined mean grip strength was lower for individuals with prediabetes than those with normoglycemia in the full sample (63.8 vs 70.9 kg; P = .004). Similar results were seen among both men (87.9 vs 82.1 kg; P = .03) and women (51.8 vs 56.5 kg; P = .001) in subgroup analysis.Conclusions: Grip strength is associated with prediabetes among healthy-weight US adults. Grip strength may have utility as an indicator for screening healthy-weight individuals for prediabetes.