RT Journal Article SR Electronic T1 Myxedema Coma In The Elderly JF The Journal of the American Board of Family Practice JO J Am Board Fam Med FD American Board of Family Medicine SP 376 OP 383 DO 10.3122/jabfm.8.5.376 VO 8 IS 5 A1 Olsen, Cynthia G. YR 1995 UL http://www.jabfm.org/content/8/5/376.abstract AB Background: Myxedema coma in the elderly, although uncommon, is frequently overlooked and has a high mortality rate. Signs and symptoms are many and are often insidious. Nearly every organ system is involved. Prompt recognition and treatment are mandatory for a successful outcome. Methods: A case study is presented. Using the key words “myxedema” with the word “aged,” MEDLINE files were searched from 1989 to present. Articles dating before 1989 were accessed from the reference lists of the more recent articles. Results and Conclusions: This review describes the signs and symptoms of myxedema coma in the elderly. Epidemiology and histopathology of the disorder are discussed. Prompt recognition and emergency medical treatment are essential for a successful outcome. Prevention requires screening of elderly patients at risk for hypothyroidism and assuring thyroid hormone replacement therapy.