PT  - JOURNAL ARTICLE
AU  - Shapiro, Joseph S.
TI  - Sarcoidosis: Current Concepts And Case Reports
AID  - 10.3122/jabfm.1.3.211
DP  - 1988 Jul 01
TA  - The Journal of the American Board of Family
                Practice
PG  - 211--217
VI  - 1
IP  - 3
4099  - http://www.jabfm.org/content/1/3/211.short
4100  - http://www.jabfm.org/content/1/3/211.full
SO  - J Am Board Fam Med1988 Jul 01; 1
AB  - Sarcoidosis is a systemic granulomatous disease of unknown etiology associated with various immune alterations and biochemical changes. This article reports recent advances in the conceptualization of the immune dysfunction with emphasis on helper T-cell overactivity in the lungs. Because 90 percent of patients with sarcoidosis have intrathoracic disease, the mode of presentation, radiographic findings, clinical course, and treatment of pulmonary involvement are discussed. Case reports are used to demonstrate the typical course of the disease and generally favorable outcome of the vast majority of patients seen in the non-referral setting. A rare case of neurosarcoidosis with neuroendocrine features is presented.