PT  - JOURNAL ARTICLE
AU  - Morrow, Robert
AU  - Nepps, Peggy
AU  - McIntosh, Margaret
TI  - Silver Acetate Mouth Spray As An Aid In Smoking Cessation: Results Of A Double-Blind Trial
AID  - 10.3122/jabfm.6.4.353
DP  - 1993 Jul 01
TA  - The Journal of the American Board of Family
                Practice
PG  - 353--357
VI  - 6
IP  - 4
4099  - http://www.jabfm.org/content/6/4/353.short
4100  - http://www.jabfm.org/content/6/4/353.full
SO  - J Am Board Fam Med1993 Jul 01; 6
AB  - Background: We studied the use of an aversive technique to improve the outcome of smoking-cessation efforts. We hypothesized that a silver acetate mouth spray, which produces a strong aversive taste when cigarettes are smoked, would increase the quit rate among smokers. Methods: Our study was a double-blind, placebo-controlled trial that was carried out in a private family practice office in an urban area. We studied 42 smokers, who were recruited by advertisement and who were motivated to quit by self-report. They were randomly assigned active spray or placebo spray; all were given a written list of behavioral suggestions. The spray was to be used every 2 hours for 3 weeks during which time the subjects were to keep diaries of cigarette smoking and spray use. Biochemical measures (salivary thiocyanate and cotinine) were recorded at entry, at 3 weeks, and at 3 months. Results: Thirty smokers completed the study. No differences were found between the two groups in quit rate or number of cigarettes smoked. Conclusions: Silver acetate aversive spray did not increase quit rate among motivated smokers.