RT Journal Article SR Electronic T1 Skin Tags — A Marker For Colon Polyps? JF The Journal of the American Board of Family Practice JO J Am Board Fam Med FD American Board of Family Medicine SP 175 OP 180 DO 10.3122/jabfm.3.3.175 VO 3 IS 3 A1 Varma, Jaydev R. YR 1990 UL http://www.jabfm.org/content/3/3/175.abstract AB The frequency of colorectal cancer increased during the first half of the twentieth century, but for the last four decades, it appears to have stabilized. Today, the average American has a 5 percent probability of developing colorectal cancer during a 70-year life span. The majority of cases occur in persons aged > 50 years; the incidence increases up to age 75 years, after which there is a decline. Etiology is unknown; however, environment, genetics, and carcinogens have been implicated. Genetic relations of skin tags, colon polyps, and colon cancer are a matter of ongoing research. If such relations could be established, it could provide clinicians with a possible additional marker for persons at increased risk of colorectal adenoma and adenocarcinoma. Two cases are presented with a brief review of the literature.