PT - JOURNAL ARTICLE AU - Bertolino, John G. TI - Diabetic Ketoacidosis And Pregnancy AID - 10.3122/jabfm.3.3.207 DP - 1990 Jul 01 TA - The Journal of the American Board of Family Practice PG - 207--215 VI - 3 IP - 3 4099 - http://www.jabfm.org/content/3/3/207.short 4100 - http://www.jabfm.org/content/3/3/207.full SO - J Am Board Fam Med1990 Jul 01; 3 AB - This paper describes the clinical course of a young diabetic primigravida who presented to her physician with vomiting and abdominal pain. Despite the conventional doses of intravenous fluid and insulin that were used to treat her suspected diabetic ketoacidosis, she remained severely acidotic and developed increasing abdominal pain. Two hundred twenty units of regular insulin over a 5-hour period were required to reverse the lipolysis, acidemia, and abdominal pain, which characterized her severe episode of diabetic ketoacidosis. This discussion emphasizes the importance of insulin in the reversal of the hyperglycemia and acidosis that accompany a diabetic crisis. The roles of bicarbonate, phosphorous, magnesium, insulin, potassium, and fluids are discussed along with conditions such as pregnancy, infection, pancreatitis, and abdominal pain, which can complicate the management of diabetic ketoacidosis.