RT Journal Article
SR Electronic
T1 Levamisole-Adulterated Cocaine: A Case Series
JF The Journal of the American Board of Family
                Medicine
JO J Am Board Fam Med
FD American Board of Family Medicine
SP 531
OP 535
DO 10.3122/jabfm.2012.04.110287
VO 25
IS 4
A1 Gerald W. Morris, Jr
A1 Bryan C. Mason
A1 Rachael Harris Sprunger
A1 Holly Hake Harris
A1 Luke A. White
A1 Dale A. Patterson
YR 2012
UL http://www.jabfm.org/content/25/4/531.abstract
AB The percentage of cocaine adulterated with levamisole is steadily increasing in the United States. In susceptible persons, this combination of drugs leads to a clinical syndrome that can include leukopenia and cutaneous manifestations. Many patients also demonstrate positive autoimmune markers. Biopsies of skin lesions often reveal a thrombotic pattern, leukocytoclastic vasculitis, or both. We report 2 cases of this clinical phenomenon, one of which was severe enough to require skin grafting. It is important for clinicians be aware of this emerging public health threat.