PT - JOURNAL ARTICLE AU - Gerald W. Morris, Jr AU - Bryan C. Mason AU - Rachael Harris Sprunger AU - Holly Hake Harris AU - Luke A. White AU - Dale A. Patterson TI - Levamisole-Adulterated Cocaine: A Case Series AID - 10.3122/jabfm.2012.04.110287 DP - 2012 Jul 01 TA - The Journal of the American Board of Family Medicine PG - 531--535 VI - 25 IP - 4 4099 - http://www.jabfm.org/content/25/4/531.short 4100 - http://www.jabfm.org/content/25/4/531.full SO - J Am Board Fam Med2012 Jul 01; 25 AB - The percentage of cocaine adulterated with levamisole is steadily increasing in the United States. In susceptible persons, this combination of drugs leads to a clinical syndrome that can include leukopenia and cutaneous manifestations. Many patients also demonstrate positive autoimmune markers. Biopsies of skin lesions often reveal a thrombotic pattern, leukocytoclastic vasculitis, or both. We report 2 cases of this clinical phenomenon, one of which was severe enough to require skin grafting. It is important for clinicians be aware of this emerging public health threat.