PT  - JOURNAL ARTICLE
AU  - Morris, Gerald W.
AU  - Mason, Bryan C.
AU  - Harris Sprunger, Rachael
AU  - Hake Harris, Holly
AU  - White, Luke A.
AU  - Patterson, Dale A.
TI  - Levamisole-Adulterated Cocaine: A Case Series
AID  - 10.3122/jabfm.2012.04.110287
DP  - 2012 Jul 01
TA  - The Journal of the American Board of Family
                Medicine
PG  - 531--535
VI  - 25
IP  - 4
4099  - http://www.jabfm.org/content/25/4/531.short
4100  - http://www.jabfm.org/content/25/4/531.full
SO  - J Am Board Fam Med2012 Jul 01; 25
AB  - The percentage of cocaine adulterated with levamisole is steadily increasing in the United States. In susceptible persons, this combination of drugs leads to a clinical syndrome that can include leukopenia and cutaneous manifestations. Many patients also demonstrate positive autoimmune markers. Biopsies of skin lesions often reveal a thrombotic pattern, leukocytoclastic vasculitis, or both. We report 2 cases of this clinical phenomenon, one of which was severe enough to require skin grafting. It is important for clinicians be aware of this emerging public health threat.