TY - JOUR T1 - Levamisole-Adulterated Cocaine: A Case Series JF - The Journal of the American Board of Family Medicine JO - J Am Board Fam Med SP - 531 LP - 535 DO - 10.3122/jabfm.2012.04.110287 VL - 25 IS - 4 AU - Gerald W. Morris, Jr AU - Bryan C. Mason AU - Rachael Harris Sprunger AU - Holly Hake Harris AU - Luke A. White AU - Dale A. Patterson Y1 - 2012/07/01 UR - http://www.jabfm.org/content/25/4/531.abstract N2 - The percentage of cocaine adulterated with levamisole is steadily increasing in the United States. In susceptible persons, this combination of drugs leads to a clinical syndrome that can include leukopenia and cutaneous manifestations. Many patients also demonstrate positive autoimmune markers. Biopsies of skin lesions often reveal a thrombotic pattern, leukocytoclastic vasculitis, or both. We report 2 cases of this clinical phenomenon, one of which was severe enough to require skin grafting. It is important for clinicians be aware of this emerging public health threat. ER -