PT - JOURNAL ARTICLE AU - Jerome, Micky AU - Xakellis, George C. AU - Angstman, Greg AU - Patchin, Wayne TI - Initial Medication Selection For Treatment Of Hypertension In An Open-Panel HMO AID - 10.3122/jabfm.8.1.1 DP - 1995 Jan 01 TA - The Journal of the American Board of Family Practice PG - 1--6 VI - 8 IP - 1 4099 - http://www.jabfm.org/content/8/1/1.short 4100 - http://www.jabfm.org/content/8/1/1.full SO - J Am Board Fam Med1995 Jan 01; 8 AB - Background: During the past 25 years recommendations for treating hypertension have evolved from a stepped-care approach to monotherapy or sequential monotherapy as experience has been gained and new antihypertensive agents have been introduced. In an effort to develop a disease management strategy for hypertension, we investigated the prescribing patterns of initial medication therapy for newly treated hypertensive patients. Methods: We examined paid claims data of an open-panel HMO located in the midwest. Charts from 377 patients with newly treated hypertension from a group of 12,242 hypertensive patients in a health insurance population of 85,066 persons were studied. The type of medication regimen received by patients newly treated for hypertension during an 18-month period was categorized into monotherapy, sequential monotherapy, stepped care, and initial treatment with multiple agents. With monotherapy, the class of medication was also reported. Associations between use of angiotensin-converting enzyme (ACE) inhibitors, calcium channel blockers, or β-blockers and presence of comorbid conditions were reported. Results: Fifty-five percent of patients received monotherapy, 22 percent received stepped care, and 18 percent received sequential monotherapy. Of those 208 patients receiving monotherapy, 30 percent were prescribed a calcium channel blocker, 22 percent an ACE inhibitor, and 14 percent a β-blocker. No customization of treatment for comorbid conditions was noted. Conclusions: Physicians attempt to treat patients’ hypertension with monotherapy. In the majority of cases, they have used either a calcium channel blocker or ACE inhibitor as initial monotherapy. Costs for treating hypertension could be reduced and care improved if thiazide diuretics, a combination of potassium-sparing and thiazide diuretics, or β-blockers were used more frequently as initial monotherapy.