<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Reed, Barbara D.</style></author><author><style face="normal" font="default" size="100%">Pierson, Carl L.</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Evaluation Of A Latex Agglutination Test For The Identification Of &lt;em&gt;Candida&lt;/em&gt; Species In Vaginal Discharge</style></title><secondary-title><style face="normal" font="default" size="100%">The Journal of the American Board of Family
                Practice</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">1992</style></year><pub-dates><date><style  face="normal" font="default" size="100%">1992-07-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">375-380</style></pages><doi><style  face="normal" font="default" size="100%">10.3122/jabfm.5.4.375</style></doi><volume><style face="normal" font="default" size="100%">5</style></volume><issue><style face="normal" font="default" size="100%">4</style></issue><abstract><style  face="normal" font="default" size="100%">Background: The diagnosis of Candida vulvovaginitis using historical symptoms, pelvic examination findings, and results of traditional in-office laboratory tests is often inaccurate. Although Candida cultures can verify the diagnosis, they are not routinely used. Methods: We prospectively compared the accuracy of a commercially available, in-office, rapid, latex agglutination test (CandidaSure ™) for the identification of Candida species with results from Candida culture. Results: The sensitivity of the latex agglutination test was 66 percent and the specificity was 63 percent when compared with Candida culture results in patients with vaginal symptoms. When compared with a microscopic evaluation using potassium hydroxide (KOH), the CandidaSure ™ test had greater sensitivity but a lower specificity. In 74 percent of cases with a positive KOH preparation, yeast forms were present on culture, and little was gained by adding the CandidaSure ™ test in this situation. The addition of the CandidaSure ™ test in those cases with a negative KOH preparation resulted in increased sensitivity but also increased the number of false-positive diagnoses. Conclusions: The CandidaSure ™ test has greater sensitivity than the KOH preparation, but it is less predictive of a positive culture. Because of this limitation, Candida should be documented by culture for any patient who has recurrent or persistent disease and a negative KOH slide.</style></abstract></record></records></xml>