RT Journal Article SR Electronic T1 Use Effectiveness Of The Cytobrush ™ In The Primary Care Setting JF The Journal of the American Board of Family Practice JO J Am Board Fam Med FD American Board of Family Medicine SP 365 OP 368 DO 10.3122/jabfm.5.4.365 VO 5 IS 4 A1 Cauthen, Don B. A1 Cullison, Mark A1 Symm, Barbalee A1 Peterson, Robert F. YR 1992 UL http://www.jabfm.org/content/5/4/365.abstract AB Background: Numerous studies indicate that Papanicolaou smears contain better cellular material when the technique for collecting the sample employs the Zelsmyn Cytobrush ™. Few studies, however, have examined its ability to increase the percentage of abnormal Papanicolaou smear results in actual clinical practice. Methods: This study looked at 7999 Papanicolaou smears done by 46 primary care physicians to determine the percentage of abnormal results during two different periods. The Cytobrush ™ technique was then implemented; and after 6029 Papanicolaou smears, the percentage of smears with abnormal findings was recalculated. Results: The proportion of Papanicolaou smears demonstrating significantly abnormal cells remained constant during the three observation periods: 1.81 percent during the first period, 1.96 percent during the second period (before the Cytobrush ™ technique was implemented), and 1.96 percent during the third period (after the Cytobrush ™ technique was implemented). Conclusions: It seems logical that Papanicolaou smears containing better cellular material from the squamocolumnar Junction would increase the yield of Papanicolaou smears with cancerous and precancerous cells. Our study, however, did not confirm this supposition. While evaluation of Papanicolaou smear technique based on quantity and quality of cellular material is important, we believe the effectiveness of any technique must be evaluated from another perspective — the actual practice setting.