RT Journal Article
SR Electronic
T1 Post-Transfusion Purpura
JF The Journal of the American Board of Family
                Practice
JO J Am Board Fam Med
FD American Board of Family Medicine
SP 175
OP 177
DO 10.3122/jabfm.4.3.175
VO 4
IS 3
A1 Vincent, E. Chris
A1 Willett, Tracy
YR 1991
UL http://www.jabfm.org/content/4/3/175.abstract
AB Post-transfusion purpura is a complication of blood product transfusion in which the recipient produces antiplatelet antibodies resulting in severe thrombocytopenia. The typical patient is a multiparous woman who develops sudden severe purpura 1 week after receiving a transfusion of packed red cells or whole blood. Post-transfusion purpura should, however, be considered in any patient with thrombocytopenia following infusion of a blood product. Untreated, the disease can be fatal or cause serious morbidity. Treatment options include plasmapheresis, intravenous immunoglobulin, and corticosteroids. Platelet transfusion is usually unsuccessful.