PT - JOURNAL ARTICLE AU - Vincent, E. Chris AU - Willett, Tracy TI - Post-Transfusion Purpura AID - 10.3122/jabfm.4.3.175 DP - 1991 May 01 TA - The Journal of the American Board of Family Practice PG - 175--177 VI - 4 IP - 3 4099 - http://www.jabfm.org/content/4/3/175.short 4100 - http://www.jabfm.org/content/4/3/175.full SO - J Am Board Fam Med1991 May 01; 4 AB - Post-transfusion purpura is a complication of blood product transfusion in which the recipient produces antiplatelet antibodies resulting in severe thrombocytopenia. The typical patient is a multiparous woman who develops sudden severe purpura 1 week after receiving a transfusion of packed red cells or whole blood. Post-transfusion purpura should, however, be considered in any patient with thrombocytopenia following infusion of a blood product. Untreated, the disease can be fatal or cause serious morbidity. Treatment options include plasmapheresis, intravenous immunoglobulin, and corticosteroids. Platelet transfusion is usually unsuccessful.