RT Journal Article
SR Electronic
T1 Hydrops Fetalis Secondary to Parvovirus B19 Infections
JF The Journal of the American Board of Family Practice
JO J Am Board Fam Med
FD American Board of Family Medicine
SP 63
OP 68
DO 10.3122/jabfm.16.1.63
VO 16
IS 1
A1 Jin Xu
A1 Thomas C. Raff
A1 Nabil S. Muallem
A1 A. George Neubert
YR 2003
UL http://www.jabfm.org/content/16/1/63.abstract
AB Background: Fetal infection by human parvovirus B19 is a common cause of fetal anemia, nonimmune hydrops fetalis, and spontaneous abortion and can result in fetal death. Recent improvements in diagnosing parvovirus infections and the availability of intrauterine transfusion have reduced the overall rate of fetal loss after maternal exposure.Methods: We report two cases of maternal parvovirus infection with classic findings of hydrops fetalis and review various aspects of parvovirus infection with emphasis on the developing management options in pregnancy.Results and Conclusions: Different management led to different results. In the first case there was normal neonatal and infantile development, and in the second case, the fetus died. With accurate laboratory testing, obstetric sonography, and fetal transfusion, the fetal mortality from parvovirus infection has been reduced considerably, and most pregnancies complicated by maternal parvovirus infection result in healthy outcomes.