RT Journal Article SR Electronic T1 Secondary Hyperparathyroidism: Pathophysiology and Treatment JF The Journal of the American Board of Family Medicine JO J Am Board Fam Med FD American Board of Family Medicine SP 574 OP 581 DO 10.3122/jabfm.2009.05.090026 VO 22 IS 5 A1 Wissam Saliba A1 Boutros El-Haddad YR 2009 UL http://www.jabfm.org/content/22/5/574.abstract AB Secondary hyperparathyroidism is a frequently encountered problem in the management of patients with chronic kidney disease (CKD). Its pathophysiology is mainly due to hyperphosphatemia and vitamin D deficiency and resistance. This condition has a high impact on the mortality and morbidity of dialysis patients. Early diagnosis of secondary hyperparathyroidism is crucial in the management of patients with CKD. The treatment remains a challenge for patients and their clinicians. It should include a combination of dietary phosphorus restriction, phosphate binders, vitamin D analogues, and calcimimetics.