<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Matvienko, Oksana A.</style></author><author><style face="normal" font="default" size="100%">Hoehns, James D.</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">A Lifestyle Intervention Study in Patients with Diabetes or Impaired Glucose Tolerance: Translation of a Research Intervention into Practice</style></title><secondary-title><style face="normal" font="default" size="100%">The Journal of the American Board of Family Medicine</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2009</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2009-09-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">535-543</style></pages><doi><style  face="normal" font="default" size="100%">10.3122/jabfm.2009.05.090012</style></doi><volume><style face="normal" font="default" size="100%">22</style></volume><issue><style face="normal" font="default" size="100%">5</style></issue><abstract><style  face="normal" font="default" size="100%">Objective: The objectives of this study were to translate a research-validated lifestyle modification curriculum of the Diabetes Prevention Program (DPP) into a community-based program delivered by trained graduate students on a university campus and determine whether this delivery approach is effective in lowering risk factors of type 2 diabetes in at-risk adults.Methods: A convenience sample of 29 prediabetic or type 2 diabetic patients completed a 12-month behavior modification intervention to achieve and maintain at least 7% weight loss and become more active. Changes in weight, waist and hip circumferences, blood pressure, metabolic biomarkers, physical activity levels, and medication were assessed.Results: At 6 and 12 months, 39% and 56% of patients had lost ≥5% of their weight. The mean weight loss at 12 months was 6%. Significant improvements were noted in most other anthropometric measurements and diastolic BP (−4.1 mm Hg). Significant reductions in total cholesterol (−11.7%), LDL-C (−7.6%), and HDL-C (−6.5%) were observed by 6 months but not at 12 months. Fasting glucose (−12%), systolic BP (−8.4 mm Hg), and diastolic BP (−7.0 mm Hg) were significantly improved in a subgroup of participants with at least 5% weight loss. HbA1c levels were associated with percentage weight loss. Twenty-seven percent of participants on diabetes medication had their drug discontinued.Conclusion: Weight-related findings of this study are comparable with those of the DPP. DPP curriculum implemented in a nonclinical setting can help some adults at-risk for or in early stages of diabetes improve anthropometric and certain metabolic outcomes.</style></abstract></record></records></xml>