PT - JOURNAL ARTICLE AU - Langer, Robert D. TI - Efficacy, Safety, and Tolerability of Low-Dose Hormone Therapy in Managing Menopausal Symptoms AID - 10.3122/jabfm.2009.05.080134 DP - 2009 Sep 01 TA - The Journal of the American Board of Family Medicine PG - 563--573 VI - 22 IP - 5 4099 - http://www.jabfm.org/content/22/5/563.short 4100 - http://www.jabfm.org/content/22/5/563.full SO - J Am Board Fam Med2009 Sep 01; 22 AB - Use of the lowest clinically effective dose of postmenopausal hormone therapy conforms to current recommendations and good clinical practice. Although accumulating evidence demonstrates the efficacy and tolerability of low hormone therapy doses, data about their use are limited by a lack of long-term, randomized studies. This review evaluates current evidence on the efficacy, safety, and tolerability of these preparations and their role in menopausal management.