PT  - JOURNAL ARTICLE
AU  - Viju Vijaysadan
AU  - Aphrodite M. Zimmerman
AU  - Rafael E. Pajaro
TI  - Paget-Schroetter Syndrome in the Young and Active
AID  - 10.3122/jabfm.18.4.314
DP  - 2005 Jul 01
TA  - The Journal of the American Board of Family Practice
PG  - 314--319
VI  - 18
IP  - 4
4099  - http://www.jabfm.org/content/18/4/314.short
4100  - http://www.jabfm.org/content/18/4/314.full
SO  - J Am Board Fam Med2005 Jul 01; 18
AB  - We report this case of effort thrombosis of the upper extremity (Paget-Schroetter syndrome) caused by hypertrophied muscles. This unusual cause of extrinsic venous compression and intimal injury leading to thrombosis was treated uniquely with good outcome. Untreated symptomatic patients can sustain long-term disability from venous obstruction resulting in significant loss of occupational productivity and quality of life. For the same reason, early catheter directed thrombolysis followed by anticoagulation and surgical intervention are recommended in much of the recent literature. Thrombolysis is the most common form of treatment, followed by surgery, if needed, after careful diagnostic approach. A majority of the literature supports a multimodal approach, but there is no definite consensus on management. This highlights the need for randomized clinical trials to guide management as well as to assess the safety and efficacy of anticoagulants commonly used and to define the optimal duration of therapy after thrombolysis.