RT Journal Article
SR Electronic
T1 Angioedema After Local Trauma in a Patient on Angiotensin-Converting Enzyme Inhibitor Therapy
JF The Journal of the American Board of Family Medicine
JO J Am Board Fam Med
FD American Board of Family Medicine
SP 577
OP 579
DO 10.3122/jabfm.2008.06.080103
VO 21
IS 6
A1 B. Brent Simmons
A1 Michelle A. Folsom
A1 Leslie A. Bryden
A1 James S. Studdiford
YR 2008
UL http://www.jabfm.org/content/21/6/577.abstract
AB Angioedema is a side effect that is often associated with the use of angiotensin-converting enzyme (ACE) inhibitor medications. These medications result in increased levels of circulating bradykinins. This case illustrates the result of a local traumatic event to the upper lip, presumably causing marked bradykinin release in a patient who was taking an ACE inhibitor. The local release of bradykinin from trauma, in addition to decreased bradykinin catabolism secondary to ACE inhibitor therapy, resulted in angioedema predominantly in the upper lip. The angioedema resolved with discontinuation of the ACE inhibitor.