PT  - JOURNAL ARTICLE
AU  - Scott E. Woods
AU  - Vivian Ghodsi
AU  - Amy Engel
AU  - Jeff Miller
AU  - Shama James
TI  - Serum Chromium and Gestational Diabetes
AID  - 10.3122/jabfm.2008.02.070155
DP  - 2008 Mar 01
TA  - The Journal of the American Board of Family Medicine
PG  - 153--157
VI  - 21
IP  - 2
4099  - http://www.jabfm.org/content/21/2/153.short
4100  - http://www.jabfm.org/content/21/2/153.full
SO  - J Am Board Fam Med2008 Mar 01; 21
AB  - Objective: To prospectively assess if chromium levels are different in gestational diabetics than in nondiabetic pregnant women. Therapeutic options could exist if levels are different.Methods: We conducted a 2-year prospective, gestational cohort study. The cohort included newly diagnosed pregnant patients. Two blood samples were taken, the first at consent, the second at the time of diabetes screening.Results: Five hundred eighty patients entered the cohort. One hundred fifty-five were lost to follow up and 425 patients completed the study (396 nondiabetics and 29 diabetics). The patients with gestational diabetes were significantly older, with a family history of gestational diabetes, and were significantly more likely to have been a gestational diabetic in a previous pregnancy (P < 05). There was no significant difference between the 2 groups for chromium levels both at enrollment (0.15 ± 0.06 ng/mL vs 0.14 ± 0.03 ng/mL; P = .28) and during the second trimester (0.14 ± 0.06 ng/mL vs 0.14 ± 0.04 ng/mL; P = .82).Conclusion: Serum chromium levels do not exhibit any significant variation between gestational diabetic women and nondiabetic women when assessed prospectively.