RT Journal Article SR Electronic T1 Treatment of Vasomotor Symptoms JF The Journal of the American Board of Family Medicine JO J Am Board Fam Med FD American Board of Family Medicine SP 923 OP 932 DO 10.3122/jabfm.2023.230408R1 VO 37 IS 5 A1 Atwell, Karina A1 White, Morgan A1 Kuphal, Greta A1 Williams, Makeba A1 Schrager, Sarina YR 2024 UL http://www.jabfm.org/content/37/5/923.abstract AB Vasomotor symptoms (VMS) related to the menopausal transition affect the majority of women and contribute to significant quality of life burden. Incidence, length, severity and report of symptoms vary by race, ethnicity, and coexisting health conditions. The pathophysiology of VMS is not fully understood and is likely multifactorial, involving changes in the hypothalamicpituitary-ovarian axis during the menopausal transition. Treatment approaches include lifestyle modifications, hormonal and non-hormonal therapies, including integrative and complementary medicine approaches. Systemic hormone therapy with estrogen is the most effective treatment. Emerging evidence suggests that treatment with SSRIs, SNRIs, and gabapentin is effective for many women who want to avoid hormone therapy. A shared decision approach to treatment decisions involves consideration of risks with treatment options and discussion of patient priorities.