RT Journal Article SR Electronic T1 Doxycycline Postexposure Prophylaxis for Sexually Transmitted Infection Prevention JF The Journal of the American Board of Family Medicine JO J Am Board Fam Med FD American Board of Family Medicine SP jabfm.2024.240056R0 DO 10.3122/jabfm.2024.240056R0 A1 Close, Elizabeth A1 Jones, Alexander A1 Noggle, William A2 Crawford, Paul YR 2025 UL http://www.jabfm.org/content/early/2025/01/16/jabfm.2024.240056R0.abstract AB Consider prescribing doxycycline as prophylaxis for bacterial sexually transmitted infections (STIs) in certain clinical scenarios. New data suggests that a one-time dose of 200 mg doxycycline taken within 72 hours of an unprotected sexual encounter may reduce transmission of syphilis, gonorrhea and chlamydia by a combined two thirds in a high-risk population.