PT  - JOURNAL ARTICLE
AU  - Infante, Alexander F.
AU  - Wells, Christina
AU  - Loza, Julie
AU  - Hobbs, Keia
AU  - Jarrett, Jennie B.
AU  - Elmes, Abigail T.
TI  - Be SMART About Asthma Management: Single Maintenance and Reliever Therapy
AID  - 10.3122/jabfm.2023.230456R1
DP  - 2024 Jul 01
TA  - The Journal of the American Board of Family
                Medicine
PG  - 745--752
VI  - 37
IP  - 4
4099  - http://www.jabfm.org/content/37/4/745.short
4100  - http://www.jabfm.org/content/37/4/745.full
SO  - J Am Board Fam Med2024 Jul 01; 37
AB  - Single maintenance and reliever therapy (SMART) is an asthma treatment approach that utilizes combined inhaled corticosteroids and long-acting β-agonists for maintenance and quick relief therapy. Despite the evidence for its benefits in asthma treatment and its adoption into American and international asthma guidelines and recommendations, SMART remains a practice of some debate. This article reviews the available evidence for SMART and offers guidance for its integration into comprehensive asthma management. Overall, short-acting β-agonist-only asthma therapy regimens should be avoided, regardless of condition severity (SOR A Recommendation). Family medicine clinicians should start SMART for patients requiring either GINA Step 3 or 4 therapy, especially if they have signs of poor adherence (SOR B Recommendation). Finally, use budesonide-formoterol over other inhaled corticosteroid/long-acting β-agonist combinations when implementing SMART (SOR B Recommendation).