PT  - JOURNAL ARTICLE
AU  - Williamson, Brandon
AU  - Tong, Carl
TI  - Management of Chronic Heart Failure with Reduced Ejection Fraction
AID  - 10.3122/jabfm.2023.230436R1
DP  - 2024 May 01
TA  - The Journal of the American Board of Family
                Medicine
PG  - 364--371
VI  - 37
IP  - 3
4099  - http://www.jabfm.org/content/37/3/364.short
4100  - http://www.jabfm.org/content/37/3/364.full
SO  - J Am Board Fam Med2024 May 01; 37
AB  - Heart failure with reduced ejection fraction (HFrEF) is a commonly seen clinical entity in the family physician’s practice. This clinical review focuses on the pharmacologic management of chronic HFrEF. Special attention is paid to the classification of heart failure and the newest recommendations from the American Heart Association concerning the use of guideline-directed medical therapy. β blockers, ACE inhibitors, ARBs, mineralocorticoid receptor antagonists are discussed in detail. The new emphasis on sacubitril-valsartan and SGLT2i’s as therapies for HFrEF are reviewed, followed by a brief discussion of more advanced therapies and comorbidity management.