<?xml version='1.0' encoding='UTF-8'?><xml><records><record><source-app name="HighWire" version="7.x">Drupal-HighWire</source-app><ref-type name="Journal Article">17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Stewart, Scott H</style></author><author><style face="normal" font="default" size="100%">Mainous, Arch G</style></author><author><style face="normal" font="default" size="100%">Gilbert, Greg</style></author></authors><secondary-authors></secondary-authors></contributors><titles><title><style face="normal" font="default" size="100%">Relation between alcohol consumption and C-reactive protein levels in the adult US population.</style></title><secondary-title><style face="normal" font="default" size="100%">The Journal of the American Board of Family
                Practice</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2002</style></year><pub-dates><date><style  face="normal" font="default" size="100%">2002-11-01 00:00:00</style></date></pub-dates></dates><pages><style  face="normal" font="default" size="100%">437-442</style></pages><volume><style face="normal" font="default" size="100%">15</style></volume><issue><style face="normal" font="default" size="100%">6</style></issue><abstract><style  face="normal" font="default" size="100%">BACKGROUND Moderate alcohol consumption has been linked to a decreased risk of cardiovascular death. Systemic inflammation as indicated by elevated levels of C-reactive protein might play a role in this relation.METHODS To evaluate the association of alcohol consumption with C-reactive protein, we analyzed the findings of the Third National Health and Nutrition Examination, a population-based survey representing the noninstitutionalized US population. Participants were aged 17 and older (n = 11,572). The main outcome measures studied were probability of C-reactive protein measurements being greater than 0.30 mg/dL (corresponding to the 75th percentile for the population) stratified by categories of alcohol consumption. Multivariate logistic regression was used to adjust for potential confounders.RESULTS Among nondrinkers 31% had elevated C-reactive protein levels, compared with 21% of low-to-moderate-frequency drinkers and 18% of high-frequency drinkers. In a model adjusted for confounding variables, those who drank 1 to 10 times per month (OR 0.83, 95% CI 0.72-0.95), 11 to 30 times (OR 0.74, 95% CI 0.62-0.88), and more than 60 times per month (OR 0.67, 95% CI 0.48-0.93) were less likely than nondrinkers to have elevated C-reactive protein levels.CONCLUSIONS Alcohol consumption is associated with a decreased probability of elevated C-reactive protein levels. This association supports an anti-inflammatory mechanism by which moderate alcohol use might protect against cardiovascular death.</style></abstract></record></records></xml>