RT Journal Article SR Electronic T1 Unintentional Weight Loss as the Sole Indication for Colonoscopy is Rarely Associated with Colorectal Cancer JF The Journal of the American Board of Family Medicine JO J Am Board Fam Med FD American Board of Family Medicine SP 218 OP 219 DO 10.3122/jabfm.2011.02.100166 VO 24 IS 2 A1 Ian J. Davis A1 Shannon J. Marek A1 Subbaramiah Sridhar A1 Thad Wilkins A1 Sherman M. Chamberlain YR 2011 UL http://www.jabfm.org/content/24/2/218.abstract AB Introduction: Weight loss is a commonly used indication for colonoscopy. Methods: This is a prospective case study of colonoscopies from 1998 to 2009. Descriptive statistics were used to evaluate age, sex, colonoscopy indications, and findings. Multiple logistic regression analysis was used to determine the odds of colorectal cancer (CRC) based on age, sex, and weight loss. Results: We reviewed 6425 colonoscopies. The mean age of patients was 57.4 years (SD, ±13.5 years), and 55% of patients were women. One hundred thirty-six (2.1%) of these had unintentional weight loss; for 32 patients (0.4%), unintentional weight loss was the only indication for the procedure. CRC was diagnosed in 116 patients (1.8%), but CRC was not detected in any patients for whom unintentional weight loss as the only indication for colonoscopy. Conclusion: Based on our prospective case study, unintentional weight loss alone was not associated with CRC.