PT - JOURNAL ARTICLE AU - Ian J. Davis AU - Shannon J. Marek AU - Subbaramiah Sridhar AU - Thad Wilkins AU - Sherman M. Chamberlain TI - Unintentional Weight Loss as the Sole Indication for Colonoscopy is Rarely Associated with Colorectal Cancer AID - 10.3122/jabfm.2011.02.100166 DP - 2011 Mar 01 TA - The Journal of the American Board of Family Medicine PG - 218--219 VI - 24 IP - 2 4099 - http://www.jabfm.org/content/24/2/218.short 4100 - http://www.jabfm.org/content/24/2/218.full SO - J Am Board Fam Med2011 Mar 01; 24 AB - Introduction: Weight loss is a commonly used indication for colonoscopy. Methods: This is a prospective case study of colonoscopies from 1998 to 2009. Descriptive statistics were used to evaluate age, sex, colonoscopy indications, and findings. Multiple logistic regression analysis was used to determine the odds of colorectal cancer (CRC) based on age, sex, and weight loss. Results: We reviewed 6425 colonoscopies. The mean age of patients was 57.4 years (SD, ±13.5 years), and 55% of patients were women. One hundred thirty-six (2.1%) of these had unintentional weight loss; for 32 patients (0.4%), unintentional weight loss was the only indication for the procedure. CRC was diagnosed in 116 patients (1.8%), but CRC was not detected in any patients for whom unintentional weight loss as the only indication for colonoscopy. Conclusion: Based on our prospective case study, unintentional weight loss alone was not associated with CRC.