PT - JOURNAL ARTICLE AU - Walia, Namrata AU - Matas, Jennifer AU - Turner, Acara AU - Gonzalez, Sandra AU - Zoorob, Roger TI - Yoga for Substance Use: A Systematic Review AID - 10.3122/jabfm.2021.05.210175 DP - 2021 Sep 01 TA - The Journal of the American Board of Family Medicine PG - 964--973 VI - 34 IP - 5 4099 - http://www.jabfm.org/content/34/5/964.short 4100 - http://www.jabfm.org/content/34/5/964.full SO - J Am Board Fam Med2021 Sep 01; 34 AB - Introduction: Substance use disorders (SUDs) are complex interactions between various genetic, environmental, developmental, and social factors. Yoga is recommended as a nonmainstream treatment for many health conditions, including SUDs.Methods: Five databases were searched for randomized controlled trials (RCTs) that evaluated yoga as an intervention in adults with any type of substance use disorder. The interventions being studied included Hatha yoga, Sudarshan Kriya yoga, breathing yoga exercises, and meditation. Studies, where yoga was combined with other interventions were excluded. The effect of yoga as an intervention was analyzed using primary outcomes such as anxiety, pain, and craving. Eight RCTs met the eligibility criteria, and quality analysis was conducted using the Cochrane criteria.Results: Among the 8 final studies eligible for quality analysis, 2 had undefined substance use, while the others were focused on tobacco, alcohol, or opioids. Seven out of 8 studies showed significant results and improved primary outcomes such as anxiety, pain, or substance use. Seven out of the 8 studies showed significant positive outcomes using yoga in conjunction with other pharmacological treatment modalities like opioid substitution therapy.Conclusions: Six out of 8 studies showed low concerns, while 2 studies showed some concerns about the risk of bias judgment. Although the results look encouraging, RCTs with larger sample size are needed to better evaluate the effectiveness of yoga as a treatment modality for substance use.