PT - JOURNAL ARTICLE AU - Coronado, Gloria D. AU - Thompson, Jamie H. AU - Petrik, Amanda F. AU - Nyongesa, Denis B. AU - Leo, Michael C. AU - Castillo, Melissa AU - Younger, Brittany AU - Escaron, Anne AU - Chen, Alex TI - Patient-Refined Messaging for a Mailed Colorectal Cancer Screening Program: Findings from the PROMPT Study AID - 10.3122/jabfm.2019.03.180275 DP - 2019 May 01 TA - The Journal of the American Board of Family Medicine PG - 318--328 VI - 32 IP - 3 4099 - http://www.jabfm.org/content/32/3/318.short 4100 - http://www.jabfm.org/content/32/3/318.full SO - J Am Board Fam Med2019 May 01; 32 AB - Background: Improving uptake of colorectal cancer screening has the potential of saving thousands of lives. We compared the effectiveness of automated and live prompts and reminders as part of a mailed fecal immunochemical test (FIT) outreach program.Design and Methods: Participants were 1767 adults aged 50 to 75 eyars who were not up-to-date with colorectal cancer screening recommendations at a participating community health center clinic. In addition to a mailed FIT kit, participants were randomized to receive (1) a text message prompt and 2 automated phone call reminders (automated condition); (2) up to 3 live call reminders (live condition); or (3) a text message prompt, 2 automated call reminders, and up to 3 live reminders (combined automated plus live condition). We assessed FIT completion rates in each group 6 months following randomization.Key Results: Nearly one-third of participants completed an FIT within 6 months. Compared with adults allocated to the automated condition, FIT completion rates were higher in adults allocated to the live condition (32.3% vs 26.0%; adjusted difference, 6.3 percentage points; 95% CI, 1.1–11.4) and in adults allocated to the combined automated plus live condition (35.7% vs 26.0%; adjusted difference, 9.7 percentage points; 95% CI, 4.4–14.9). The number of kits needed to mail to achieve a completed FIT ranged from 2.8 in the combined automated plus live condition to 3.8 in the automated condition.Conclusions: Among unscreened individuals in this population, live phone call reminders either alone or in combination with automated prompts and reminders outperformed automated approaches alone.