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LetterCorrespondence

Response: Re: Practical Recommendations for Minimizing Pain and Anxiety with IUD Insertion

Viktoriya Ovsepyan, Petra Kelsey and Ann E. Evensen
The Journal of the American Board of Family Medicine November 2025, 38 (6) 1139; DOI: https://doi.org/10.3122/jabfm.2025.250415R0
Viktoriya Ovsepyan
From the Viktoriya Ovsepyan, MD University of Wisconsin–Madison School of Medicine and Public Health Madison, WI 53706
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Petra Kelsey
From the Viktoriya Ovsepyan, MD University of Wisconsin–Madison School of Medicine and Public Health Madison, WI 53706
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Ann E. Evensen
From the Viktoriya Ovsepyan, MD University of Wisconsin–Madison School of Medicine and Public Health Madison, WI 53706
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We appreciate the author's interest in continuing the conversation about how best to reduce pain for patients undergoing intrauterine procedures.

Since the publication of our article,1 the American College of Obstetricians and Gynecologists has published a Clinical Consensus on Pain Management for In-Office Uterine and Cervical Procedures.2 The consensus recommendation for intrauterine device procedures states: “local anesthetic agents may reduce intrauterine device insertion.” The discussion in this Consensus regarding nonpharmacologic pain management interventions highlights a 2023 systematic review and meta-analysis of 7 RCTs involving 1,267 patients evaluating the use of transabdominal ultrasound during IUD insertion.3 This evidence is described as “promising,” reflecting both an improvement in pain scores (reduction in the Visual Analog Scale pain score of −1.91 [95% CI (−3.08, −0.73), P = .0010]) but also the limitations of this approach as it requires ultrasound equipment and a knowledgeable assistant. In addition, we note that there are now concerns about the validity of this meta-analysis as 4 of the 7 RCTs have been retracted, reducing the number of patients who could be included in analyses from 1,267 to 600.4–7

While ultrasound can be considered as one of many options to potentially reduce pain during IUD insertion, evidence for routine use to reduce pain is lacking. We encourage clinicians to discuss options for pain relief with each patient and through shared decision making determine the best plan of care.

References

  1. 1.↵
    1. Ovsepyan V,
    2. Kelsey P,
    3. Evensen A
    . Practical recommendations for minimizing pain and anxiety with IUD insertion. J Am Board Fam Med. 2024;37:1150–5.
    OpenUrlAbstract/FREE Full Text
  2. 2.↵
    Pain Management for In-Office Uterine and Cervical Procedures: ACOG Clinical Consensus No July 2025;9. Obstetrics & Gynecology 146, p161–77.
  3. 3.↵
    1. Baradwan S,
    2. Alshahrani MS,
    3. Alnoury A,
    4. et al
    . Does ultrasound guidance provide pain relief during intrauterine contraceptive device insertion? A systematic review and meta analysis of randomized controlled trials. J Ultrasound Med 2023;42:1401–11.
    OpenUrlCrossRefPubMed
  4. 4.↵
    1. Elsedeek MS
    . Comparison between the traditional non-guided and a novel ultrasound-guided technique for office fitting of intrauterine contraceptive devices. Int J Gynaecol Obstet 2016;133:338–41. Epub 2016 Feb 23. Retraction in: Int J Gynaecol Obstet 2025;168:416.
    OpenUrlPubMed
  5. 5.
    1. Dakhly DMR,
    2. Bassiouny YA
    . Ultrasound-guided intrauterine device insertion: a step closer to painless insertion: a randomized control trial. Eur J Contracept Reprod Health Care 2017;22:349–53. Epub 2017 Oct 5.Retraction in: Eur J Contracept Reprod Health Care 2023;28(3):205.
    OpenUrlPubMed
  6. 6.
    1. Maged AM,
    2. Nada AM,
    3. Abdelwahab H,
    4. et al
    . The value of ultrasound guidance during IUD insertion in women with RVF uterus: a randomized controlled trial. J Gynecol Obstet Hum Reprod 2021;50:101875. doi: 10.1016/j.jogoh.2020.101875. Epub 2020 Jul 17.Retraction in: J Gynecol Obstet Hum Reprod 2025;54:103016.
    OpenUrlCrossRefPubMed
  7. 7.↵
    1. Ali MK,
    2. Ramadan AK,
    3. Abu-Elhassan AM,
    4. Sobh AMA
    . Ultrasound-guided versus uterine sound-sparing approach during copper intrauterine device insertion: a randomised clinical trial. Eur J Contracept Reprod Health Care 2022;27:3–8. Epub 2021 Apr 15. Retraction in: Eur J Contracept Reprod Health Care 2023;28:319.
    OpenUrlPubMed
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The Journal of the American Board of Family     Medicine: 38 (6)
The Journal of the American Board of Family Medicine
Vol. 38, Issue 6
November-December 2025
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Response: Re: Practical Recommendations for Minimizing Pain and Anxiety with IUD Insertion
Viktoriya Ovsepyan, Petra Kelsey, Ann E. Evensen
The Journal of the American Board of Family Medicine Nov 2025, 38 (6) 1139; DOI: 10.3122/jabfm.2025.250415R0

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Response: Re: Practical Recommendations for Minimizing Pain and Anxiety with IUD Insertion
Viktoriya Ovsepyan, Petra Kelsey, Ann E. Evensen
The Journal of the American Board of Family Medicine Nov 2025, 38 (6) 1139; DOI: 10.3122/jabfm.2025.250415R0
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